Antibody R&D, one step at a time
MImAbs platform can be accessed in stretches for a service-on-demand approach where only part of MImAbs’ offer is contracted, when and if required. MImAbs offers two types of R&D Services: catalog or customized services.
Catalogue services corresponds to well defined R&D steps readily available, have a fixed price and can either be performed under contract or with a purchase order, depending on the extent of work required:
Recombinant mAb generation (generation of rodent single B cells, cloning of VH and VL, sequencing, humanization)
mAb bioproduction (from mg scale to gram scale)
Generation of ADCs
In vitro mAb validation using ADCC and ADCC-like assays
In vitro/in vivo validation of bi-specific antibodies engaging human CD3ɛ
Combination with anti-PD1/anti-CTLA4 on syngeneic mouse models
Customized stretches often require set up experiments, need to be performed under contract and will be priced in cost-per-work packages.